Human protein Beta-2-microglobulin

URI: https://gptkb.org/entity/Human_protein_Beta-2-microglobulin
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:B2M
beta-2-microglobulin
CDABP0092
gptkbp:component MHC class I molecule
gptkbp:disorderAssociation amyloidosis
dialysis-related amyloidosis
gptkbp:Entrez_Gene_ID 567
ENSG00000166710
gptkbp:expressedIn all nucleated cells
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function involved in immune response
antigen binding
gptkbp:gene gptkb:B2M
gptkbp:GOProcess immune system process
gptkbp:HGNC_ID 914
https://www.w3.org/2000/01/rdf-schema#label Human protein Beta-2-microglobulin
gptkbp:length 119 amino acids
gptkbp:locatedOnChromosome 15q21-q22
gptkbp:molecularWeight 11.8 kDa
gptkbp:OMIM 109700
gptkbp:PDB 1LDS
gptkbp:postTranslationalModification disulfide bond
gptkbp:RefSeq NP_004039.2
gptkbp:significance elevated in chronic kidney disease
elevated in multiple myeloma
marker for renal function
gptkbp:structure single polypeptide chain
gptkbp:subcellularLocation gptkb:cell_membrane
extracellular space
gptkbp:UniProtID P61769
gptkbp:bfsParent gptkb:P0CG47
gptkbp:bfsLayer 7