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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:abbreviation
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gptkb:HSA
|
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gptkbp:allergenicity
|
low
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gptkbp:alternativeName
|
gptkb:ALB
gptkb:serum_albumin
gptkb:albumin,_serum
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gptkbp:associatedWith
|
malnutrition
shock
edema
dehydration
burns
chronic kidney disease
liver cirrhosis
nephrotic syndrome
acute liver failure
hypoalbuminemia
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gptkbp:binds
|
drugs
calcium
thyroxine
fatty acids
bilirubin
|
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gptkbp:concentrationInPlasma
|
35-50 g/L
|
|
gptkbp:degradedBy
|
gptkb:skeletal_muscle
gptkb:kidney
liver
|
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gptkbp:encodedBy
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gptkb:ALB_gene
|
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gptkbp:firstDescribed
|
1939
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|
gptkbp:foundIn
|
human blood plasma
|
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gptkbp:function
|
maintains oncotic pressure
transports drugs
transports fatty acids
transports hormones
|
|
gptkbp:glycosylation
|
non-glycosylated
|
|
gptkbp:halfLife
|
about 19 days
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Human Serum Albumin
|
|
gptkbp:locatedOnChromosome
|
4q13.3
|
|
gptkbp:medicalUse
|
treatment of burns
treatment of hypoalbuminemia
treatment of shock
volume expander
|
|
gptkbp:molecularWeight
|
about 66.5 kDa
|
|
gptkbp:PDB
|
gptkb:1AO6
|
|
gptkbp:pI
|
4.7
|
|
gptkbp:sequence
|
585 amino acids
|
|
gptkbp:structure
|
single polypeptide chain
|
|
gptkbp:synthesisType
|
liver
|
|
gptkbp:UniProtID
|
gptkb:P02768
|
|
gptkbp:usedIn
|
laboratory diagnostics
cell culture
pharmaceutical formulations
|
|
gptkbp:bfsParent
|
gptkb:HSA
|
|
gptkbp:bfsLayer
|
6
|