|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:basicAminoAcids
|
Arginine
Lysine
|
|
gptkbp:compatibleWith
|
Most prokaryotes
|
|
gptkbp:component
|
Nucleosome
|
|
gptkbp:conservedIn
|
gptkb:Eukaryotes
|
|
gptkbp:discoveredBy
|
gptkb:Albrecht_Kossel
|
|
gptkbp:discoveredIn
|
1884
|
|
gptkbp:encodedBy
|
Histone genes
|
|
gptkbp:form
|
Nucleosome core particle
Octamer
|
|
gptkbp:foundIn
|
gptkb:Eukaryotic_cells
|
|
gptkbp:function
|
Gene regulation
DNA packaging
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Histones
|
|
gptkbp:interactsWith
|
gptkb:gene
Chromatin remodeling complexes
|
|
gptkbp:location
|
Cell nucleus
|
|
gptkbp:mass
|
~11-21 kDa
|
|
gptkbp:postTranslationalModification
|
Methylation
Phosphorylation
Acetylation
Ubiquitination
|
|
gptkbp:role
|
gptkb:Epigenetics
DNA repair
Transcription regulation
Cell cycle
Chromatin structure
|
|
gptkbp:solubility
|
Water-soluble
|
|
gptkbp:structure
|
Alpha helix
|
|
gptkbp:subjectOf
|
Cancer research
Developmental biology
Chromatin research
Epigenetic therapy
Histone code hypothesis
|
|
gptkbp:type
|
gptkb:H1
H3
H4
H2A
H2B
|
|
gptkbp:bfsParent
|
gptkb:Nucleus_(in_mammals)
gptkb:Nuclei
|
|
gptkbp:bfsLayer
|
7
|