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gptkbp:instanceOf
|
genetic disorder
bleeding disorder
|
|
gptkbp:affects
|
mostly males
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|
gptkbp:alsoKnownAs
|
gptkb:Christmas_disease
|
|
gptkbp:complication
|
hemarthrosis
intracranial hemorrhage
muscle hematoma
|
|
gptkbp:deficiencyCauses
|
gptkb:factor_IX
|
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gptkbp:diagnosedBy
|
genetic testing
factor IX assay
|
|
gptkbp:firstDescribed
|
1952
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|
https://www.w3.org/2000/01/rdf-schema#label
|
Hemophilia B
|
|
gptkbp:ICD-10_code
|
D66
|
|
gptkbp:inheritance
|
X-linked recessive
|
|
gptkbp:mainCarriers
|
females
|
|
gptkbp:MeSH_ID
|
D006467
|
|
gptkbp:mutationAssociatedWith
|
gptkb:F9_gene
|
|
gptkbp:namedAfter
|
gptkb:Stephen_Christmas
|
|
gptkbp:notableCase
|
gptkb:Queen_Victoria's_descendants
|
|
gptkbp:OMIM
|
306900
|
|
gptkbp:prevalence
|
1 in 25,000 male births
|
|
gptkbp:riskFactor
|
family history of hemophilia
|
|
gptkbp:subspecies
|
mild hemophilia B
moderate hemophilia B
severe hemophilia B
|
|
gptkbp:symptom
|
prolonged bleeding
joint bleeding
spontaneous bleeding
|
|
gptkbp:treatment
|
factor IX replacement therapy
recombinant factor IX
|
|
gptkbp:bfsParent
|
gptkb:Hemophilia_A
gptkb:Gene_Therapy
gptkb:P00797
|
|
gptkbp:bfsLayer
|
7
|