Properties (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:associatedWith |
severe bleeding episodes
|
| gptkbp:canBe |
chronic pain
joint damage |
| gptkbp:canLeadTo |
hemarthrosis
life-threatening bleeding intracranial_hemorrhage |
| gptkbp:causedBy |
deficiency of factor IX
|
| gptkbp:demographics |
1 in 25,000 male births
|
| gptkbp:diseaseResistance |
blood tests
|
| gptkbp:established |
gptkb:Dr._Stephen_Christmas
|
| gptkbp:firstDescribedBy |
1936
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hemophilia B
|
| gptkbp:impact |
blood clotting
desmopressin factor_IX_replacement_therapy |
| gptkbp:influencedBy |
males more than females
|
| gptkbp:isAssociatedWith |
psychosocial issues
increased risk of surgery complications |
| gptkbp:isCharacterizedBy |
deficiency in clotting factor IX
|
| gptkbp:isConsidered |
a rare disease
|
| gptkbp:isCounteredBy |
quality of life
|
| gptkbp:isDocumentedIn |
medical literature
|
| gptkbp:isEvaluatedBy |
specialized_clinics
|
| gptkbp:isFoundIn |
people_of_Northern_European_descent
|
| gptkbp:isLedBy |
people_of_African_descent
|
| gptkbp:isLinkedTo |
family history
|
| gptkbp:isMaintainedBy |
genetic mutations
|
| gptkbp:isManagedBy |
patient education
gene therapy hematologists prophylactic treatment |
| gptkbp:isPartOf |
genetic counseling
bleeding disorders hemophilia_spectrum_disorders |
| gptkbp:isRecognizedBy |
health organizations
|
| gptkbp:isStudiedIn |
clinical trials
|
| gptkbp:isSupportedBy |
patient advocacy groups
|
| gptkbp:isUsedFor |
gptkb:recombinant_factor_IX
gptkb:plasma-derived_factor_IX physical therapy viral infections inhibitors antifibrinolytics emergency care for bleeding episodes |
| gptkbp:nobleFamily |
X-linked recessive
|
| gptkbp:previouslyKnownAs |
Christmas disease
|
| gptkbp:relatedPatent |
hemophilia A
|
| gptkbp:requires |
regular check-ups
|
| gptkbp:research |
available
|
| gptkbp:screenings |
factor IX activity test
|
| gptkbp:symptoms |
joint pain
easy bruising prolonged bleeding |