HTLV-1

GPTKB entity

Statements (82)
Predicate Object
gptkbp:instance_of gptkb:virus
gptkbp:affects gptkb:humans
gptkbp:associated_with gptkb:adult_T-cell_leukemia
gptkb:HTLV-1-associated_myelopathy
gptkbp:cause gptkb:Adult_T-cell_leukemia
gptkbp:clinical_trial ongoing research
gptkbp:co-infection_risk gptkb:HIV
gptkb:hepatitis_C
gptkbp:community_health yes
in endemic regions
gptkbp:core_protein p19
p24
gptkbp:diagnosis PCR
serological tests
serological testing
PCR testing
gptkbp:discovered_by gptkb:Robert_Gallo
1970s
gptkbp:discovery_year gptkb:1980
gptkbp:diseases gptkb:Oncology
gptkb:HTLV-1-associated_myelopathy
gptkbp:envelope_protein gp21
gp46
gptkbp:epidemiology ongoing research
endemic in certain regions
global health concern
gptkbp:field_of_study oncology
virology
gptkbp:first_described_by gptkb:Africa
gptkb:Japan
gptkb:United_States
gptkbp:geographic_distribution gptkb:Caribbean
gptkb:Japan
gptkb:South_America
gptkbp:grooming_needs can be high in infected individuals
gptkbp:hosts gptkb:humans
https://www.w3.org/2000/01/rdf-schema#label HTLV-1
gptkbp:is_recognized_as a patient in the United States
gptkbp:is_vulnerable_to no vaccine available
gptkbp:origin gptkb:Japan
gptkbp:performance can remain dormant
gptkbp:prevalence higher in certain regions
1-5% in endemic areas
gptkbp:prevention safe sex practices
avoid sharing needles
screening blood donors
avoidance of breastfeeding in infected mothers
gptkbp:propagation_method breastfeeding
sexual contact
blood transfusion
gptkbp:related_to gptkb:HTLV-3
gptkb:HTLV-4
gptkb:HTLV-2
gptkbp:replaces T-cells
T-cell leukemia patient
a patient with T-cell leukemia
gptkbp:reprints gptkb:Atom
gptkbp:research associated with inflammatory diseases
linked to increased risk of certain cancers
gptkbp:research_focus HIV co-infection
gptkbp:risk_factor immunosuppression
multiple sexual partners
mother-to-child transmission
intravenous drug use
co-infection with HIV
gptkbp:seed_dispersal single-stranded RNA
gptkbp:symptoms dermatitis
neurological disorders
asymptomatic in many cases
myelopathy
gptkbp:transmission breastfeeding
sexual contact
blood transfusion
gptkbp:treatment supportive care
no specific antiviral treatment
no cure
antiviral therapy under study
gptkbp:type retrovirus
gptkbp:vector insect bites (theoretical)
gptkbp:viral_load_measurement plasma viral load
gptkbp:bfsParent gptkb:Retroviridae
gptkbp:bfsLayer 5