|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
prostate cancer
|
|
gptkbp:biologicalProcess
|
DNA binding
anterior/posterior pattern specification
prostate gland development
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodes
|
Homeobox protein Hox-B13
|
|
gptkbp:Entrez_Gene_ID
|
2849
ENSG00000159184
|
|
gptkbp:expressedIn
|
gptkb:skin
gptkb:prostate
colon
|
|
gptkbp:fullName
|
homeobox B13
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:G84EvariantAssociatedWith
|
increased prostate cancer risk
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:has3PrimeUTR
|
yes
|
|
gptkbp:has5PrimeUTR
|
yes
|
|
gptkbp:hasParalog
|
gptkb:HOXB1
gptkb:HOXB2
gptkb:HOXB3
gptkb:HOXB4
gptkb:HOXB5
gptkb:HOXB6
gptkb:HOXB7
gptkb:HOXB8
gptkb:HOXB9
|
|
gptkbp:hasVariant
|
G84E
|
|
gptkbp:HGNC_ID
|
5102
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HOXB13
|
|
gptkbp:involvedIn
|
developmental processes
|
|
gptkbp:length
|
284 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_17
|
|
gptkbp:memberOf
|
gptkb:homeobox_gene_family
|
|
gptkbp:mutationAssociatedWith
|
hereditary prostate cancer
|
|
gptkbp:numberOfExons
|
2
|
|
gptkbp:OMIM
|
604607
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Hoxb13
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
androgen receptor signaling
|
|
gptkbp:relatedTo
|
HOX gene cluster
|
|
gptkbp:transcriptionRegulator
|
true
|
|
gptkbp:transcriptionStartSite
|
chr17:48,673,000 (GRCh38)
|
|
gptkbp:UniProtID
|
Q92826
|
|
gptkbp:bfsParent
|
gptkb:HOXB
|
|
gptkbp:bfsLayer
|
8
|