Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:affects |
HER2 gene
|
| gptkbp:alsoKnownAs |
ERBB2 mutations
|
| gptkbp:associatedWith |
gptkb:cancer
gastric cancer |
| gptkbp:canBeGermline |
true
|
| gptkbp:canBeSomatic |
true
|
| gptkbp:canConfer |
resistance to some therapies
|
| gptkbp:cause |
uncontrolled cell growth
overexpression of HER2 protein |
| gptkbp:detects |
gptkb:fluorescence_in_situ_hybridization
next-generation sequencing immunohistochemistry |
| https://www.w3.org/2000/01/rdf-schema#label |
HER2 mutations
|
| gptkbp:target |
gptkb:afatinib
gptkb:ado-trastuzumab_emtansine gptkb:pertuzumab gptkb:trastuzumab gptkb:lapatinib gptkb:neratinib |
| gptkbp:bfsParent |
gptkb:InVisionFirst-Lung
|
| gptkbp:bfsLayer |
8
|