HEPN domains

GPTKB entity

Statements (21)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation Higher Eukaryotes and Prokaryotes Nucleotide-binding domain
gptkbp:associatedWith toxin-antitoxin systems
gptkbp:discoveredIn 2000s
gptkbp:example gptkb:Cas13
MazF
RnlA
gptkbp:foundIn gptkb:Bacteria
proteins
archaea
eukaryotes
gptkbp:function cellular stress response
antiviral defense
nuclease activity
https://www.w3.org/2000/01/rdf-schema#label HEPN domains
gptkbp:involvedIn RNA processing
gptkbp:motif Rx4-6H
gptkbp:relatedTo gptkb:CRISPR-Cas_systems
gptkbp:structure alpha-helical fold
gptkbp:bfsParent gptkb:CRISPR-Cas13_family
gptkbp:bfsLayer 8