Guanine phosphoribosyltransferase

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:abbreviation GPRT
gptkbp:alternativeName hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
gptkbp:associatedWith gptkb:Lesch-Nyhan_syndrome
gptkbp:biologicalProcess transferase activity
purine salvage pathway
gptkbp:CASNumber 9030-21-1
gptkbp:catalyzes guanine + PRPP ⇌ GMP + pyrophosphate
gptkbp:cofactor Mg2+
gptkbp:EC_number 2.4.2.8
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:gene HPRT1
gptkbp:GO_term GO:0004371
https://www.w3.org/2000/01/rdf-schema#label Guanine phosphoribosyltransferase
gptkbp:product pyrophosphate
guanosine monophosphate (GMP)
gptkbp:substrate guanine
phosphoribosyl pyrophosphate (PRPP)
gptkbp:UniProtID P00492
gptkbp:bfsParent gptkb:GPB
gptkbp:bfsLayer 7