Guanine phosphoribosyltransferase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
GPRT
|
| gptkbp:alternativeName |
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
|
| gptkbp:associatedWith |
gptkb:Lesch-Nyhan_syndrome
|
| gptkbp:biologicalProcess |
transferase activity
purine salvage pathway |
| gptkbp:CASNumber |
9030-21-1
|
| gptkbp:catalyzes |
guanine + PRPP ⇌ GMP + pyrophosphate
|
| gptkbp:cofactor |
Mg2+
|
| gptkbp:EC_number |
2.4.2.8
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
| gptkbp:gene |
HPRT1
|
| gptkbp:GO_term |
GO:0004371
|
| gptkbp:product |
pyrophosphate
guanosine monophosphate (GMP) |
| gptkbp:substrate |
guanine
phosphoribosyl pyrophosphate (PRPP) |
| gptkbp:UniProtID |
P00492
|
| gptkbp:bfsParent |
gptkb:GPB
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
Guanine phosphoribosyltransferase
|