Guanine phosphoribosyltransferase
GPTKB entity
Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:abbreviation |
GPRT
|
gptkbp:alternativeName |
hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
|
gptkbp:associatedWith |
gptkb:Lesch-Nyhan_syndrome
|
gptkbp:biologicalProcess |
transferase activity
purine salvage pathway |
gptkbp:CASNumber |
9030-21-1
|
gptkbp:catalyzes |
guanine + PRPP ⇌ GMP + pyrophosphate
|
gptkbp:cofactor |
Mg2+
|
gptkbp:EC_number |
2.4.2.8
|
gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
gptkbp:gene |
HPRT1
|
gptkbp:GO_term |
GO:0004371
|
https://www.w3.org/2000/01/rdf-schema#label |
Guanine phosphoribosyltransferase
|
gptkbp:product |
pyrophosphate
guanosine monophosphate (GMP) |
gptkbp:substrate |
guanine
phosphoribosyl pyrophosphate (PRPP) |
gptkbp:UniProtID |
P00492
|
gptkbp:bfsParent |
gptkb:GPB
|
gptkbp:bfsLayer |
7
|