|
gptkbp:instanceOf
|
biological pathway
|
|
gptkbp:activatedBy
|
gptkb:AMP
gptkb:fructose_2,6-bisphosphate
|
|
gptkbp:alternativeName
|
gptkb:Embden-Meyerhof-Parnas_pathway
|
|
gptkbp:anaerobic
|
true
|
|
gptkbp:connectsTo
|
fermentation
cellular respiration
|
|
gptkbp:discoveredBy
|
gptkb:Otto_Meyerhof
gptkb:Gustav_Embden
Jakub Parnas
|
|
gptkbp:energyInvestmentPhase
|
true
|
|
gptkbp:energyPayoffPhase
|
true
|
|
gptkbp:firstStepEnzyme
|
gptkb:hexokinase
|
|
gptkbp:followedBy
|
fermentation (in absence of oxygen)
pyruvate oxidation
|
|
gptkbp:foundIn
|
prokaryotes
eukaryotes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Glycolysis
|
|
gptkbp:inhibitedBy
|
gptkb:ATP
citrate
|
|
gptkbp:involves
|
phosphorylation
oxidation
cleavage
dephosphorylation
isomerization
|
|
gptkbp:irreversibleStepEnzyme
|
gptkb:hexokinase
gptkb:pyruvate_kinase
phosphofructokinase-1
|
|
gptkbp:irreversibleSteps
|
3
|
|
gptkbp:lastStepEnzyme
|
gptkb:pyruvate_kinase
|
|
gptkbp:mainFunction
|
glucose breakdown
|
|
gptkbp:netATPProducedPerGlucose
|
2
|
|
gptkbp:netNADHProducedPerGlucose
|
2
|
|
gptkbp:netPyruvateProducedPerGlucose
|
2
|
|
gptkbp:occurredIn
|
gptkb:cytoplasm
|
|
gptkbp:precededBy
|
glucose transport
|
|
gptkbp:produces
|
2 water molecules per glucose
intermediates for biosynthesis
metabolic heat
|
|
gptkbp:product
|
gptkb:ATP
gptkb:pyruvate
gptkb:NADH
|
|
gptkbp:regulatoryEnzyme
|
phosphofructokinase-1
|
|
gptkbp:requires
|
anaerobic metabolism
red blood cell energy production
|
|
gptkbp:reversibleSteps
|
7
|
|
gptkbp:step
|
10
|
|
gptkbp:substrate
|
glucose
|
|
gptkbp:substrateLevelPhosphorylation
|
true
|
|
gptkbp:usedBy
|
all living cells
|
|
gptkbp:bfsParent
|
gptkb:P42127
gptkb:Gluconeogenesis
|
|
gptkbp:bfsLayer
|
7
|