Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
|
gptkbp:approvalYear |
2019
|
gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
gptkbp:ATCCode |
L04AX08
|
gptkbp:form |
gptkb:government_agency
solution for injection |
gptkbp:genericName |
gptkb:givosiran
|
https://www.w3.org/2000/01/rdf-schema#label |
Givlaari
|
gptkbp:indication |
gptkb:acute_hepatic_porphyria
|
gptkbp:legalStatus |
prescription only
|
gptkbp:manufacturer |
gptkb:Alnylam_Pharmaceuticals
|
gptkbp:mechanismOfAction |
gptkb:RNA_interference
|
gptkbp:pregnancyCategory |
unknown
|
gptkbp:routeOfAdministration |
subcutaneous injection
|
gptkbp:sideEffect |
nausea
fatigue injection site reaction rash elevated liver enzymes |
gptkbp:target |
aminolevulinate synthase 1 (ALAS1)
|
gptkbp:bfsParent |
gptkb:Alnylam_Pharmaceuticals
|
gptkbp:bfsLayer |
6
|