Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
small interfering RNA |
gptkbp:administeredBy |
subcutaneous injection
|
gptkbp:approvalYear |
2019
|
gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
gptkbp:ATCCode |
N07XX14
|
gptkbp:brand |
gptkb:Givlaari
|
gptkbp:CASNumber |
1446321-46-5
|
gptkbp:chemicalFormula |
C204H267F9N60O80P19S
|
gptkbp:developer |
gptkb:Alnylam_Pharmaceuticals
|
https://www.w3.org/2000/01/rdf-schema#label |
givosiran
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
inhibits aminolevulinic acid synthase 1 (ALAS1)
|
gptkbp:routeOfAdministration |
subcutaneous
|
gptkbp:sideEffect |
nausea
fatigue injection site reaction rash increased liver enzymes |
gptkbp:usedFor |
gptkb:acute_hepatic_porphyria
|
gptkbp:bfsParent |
gptkb:Givlaari
|
gptkbp:bfsLayer |
7
|