General transcription factor IIB

URI: https://gptkb.org/entity/General_transcription_factor_IIB
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
transcription factor
gptkbp:alternativeName gptkb:TFIIB
transcription factor IIB
gptkbp:conservedIn eukaryotes
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function transcription initiation
RNA polymerase II preinitiation complex assembly
gptkbp:gene gptkb:GTF2B
gptkbp:gene_location_(human) gptkb:14q32.2
https://www.w3.org/2000/01/rdf-schema#label General transcription factor IIB
gptkbp:interactsWith gptkb:RNA_polymerase_II
gptkb:TFIIF
gptkb:TBP
gptkbp:molecularWeight ~35 kDa
gptkbp:OMIM 189963
gptkbp:orthologInMouse Gtf2b
gptkbp:orthologInYeast SUA7
gptkbp:participatedIn transcription regulation
gptkbp:PDB 1VOL
gptkbp:regulates gene expression
gptkbp:requires transcription by RNA polymerase II
promoter clearance
start site selection
gptkbp:reviewedBy gptkb:GeneCards
gptkb:UniProt
gptkbp:structure contains core domain
contains zinc ribbon domain
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:UniProtID Q00403
gptkbp:bfsParent gptkb:TFIIB
gptkbp:bfsLayer 7