Gene Set Enrichment Analysis

GPTKB entity

Statements (45)
Predicate Object
gptkbp:instanceOf bioinformatics method
gptkbp:abbreviation gptkb:GSEA
gptkbp:alternativeTo gptkb:DAVID
gptkb:Enrichr
GO enrichment analysis
gptkbp:analyzes gptkb:RNA-seq_data
gene sets
microarray data
gptkbp:canBe cancer research
drug discovery
disease mechanism studies
gptkbp:citation Subramanian, A. et al. (2005) PNAS 102(43):15545-15550
gptkbp:developedBy gptkb:Eric_S._Lander
gptkb:Jill_P._Mesirov
gptkb:Aravind_Subramanian
gptkb:J.P._Mesirov
gptkb:Pablo_Tamayo
gptkb:Vamsi_K._Mootha
https://www.w3.org/2000/01/rdf-schema#label Gene Set Enrichment Analysis
gptkbp:input ranked list of genes
gptkbp:license free for academic use
gptkbp:output enrichment score
false discovery rate
significance p-value
gptkbp:platform gptkb:Java
gptkb:mobile_application
command line
gptkbp:publishedIn gptkb:Proceedings_of_the_National_Academy_of_Sciences
2005
gptkbp:recognizedBy biological pathways
functional gene sets
gptkbp:relatedTo systems biology
functional genomics
gene ontology
gptkbp:requires gene expression profiles
gene set database
gptkbp:software_available_at gptkb:Broad_Institute
gptkbp:supports gptkb:MSigDB_gene_sets
gptkbp:type gptkb:permutation_test
statistical analysis
Kolmogorov-Smirnov-like statistic
gptkbp:usedFor interpreting gene expression data
gptkbp:website https://www.gsea-msigdb.org/
gptkbp:bfsParent gptkb:Jill_P._Mesirov
gptkbp:bfsLayer 6