Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
|
gptkbp:approvalYear |
2020
|
gptkbp:approvedBy |
gptkb:FDA
|
gptkbp:ATCCode |
L01EX21
|
gptkbp:brand |
gptkb:Gavreto
|
gptkbp:CASNumber |
2097132-83-2
|
gptkbp:chemicalFormula |
C27H32N6O3
|
gptkbp:developer |
gptkb:Roche
gptkb:Blueprint_Medicines |
gptkbp:form |
capsule
|
gptkbp:genericName |
gptkb:pralsetinib
|
https://www.w3.org/2000/01/rdf-schema#label |
Gavreto
|
gptkbp:indication |
gptkb:RET_fusion-positive_cancers
|
gptkbp:legalStatus |
Rx-only
|
gptkbp:mechanismOfAction |
RET kinase inhibitor
|
gptkbp:molecularWeight |
488.58 g/mol
|
gptkbp:pregnancyCategory |
not recommended
|
gptkbp:prescriptionStatus |
prescription only
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
gptkb:anemia
constipation fatigue hypertension increased liver enzymes |
gptkbp:target |
gptkb:RET_proto-oncogene
|
gptkbp:usedFor |
gptkb:non-small_cell_lung_cancer
gptkb:RET_fusion-positive_thyroid_cancer |
gptkbp:bfsParent |
gptkb:pralsetinib
|
gptkbp:bfsLayer |
6
|