Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alias |
gptkb:TFIIB
TF2B |
gptkbp:alternativeSplicing |
yes
|
gptkbp:associatedWith |
transcription regulation
|
gptkbp:biologicalProcess |
gene expression
transcription factor activity |
gptkbp:cellularComponent |
gptkb:nucleus
|
gptkbp:discoveredBy |
1992
|
gptkbp:encodes |
GTF2B protein
|
gptkbp:Entrez_Gene_ID |
2959
ENSG00000125818 |
gptkbp:expressedIn |
various tissues
|
gptkbp:fullName |
general transcription factor IIB
|
gptkbp:function |
transcription initiation
RNA polymerase II preinitiation complex assembly |
gptkbp:HGNC_ID |
HGNC:4642
|
https://www.w3.org/2000/01/rdf-schema#label |
GTF2B gene
|
gptkbp:interactsWith |
gptkb:RNA_polymerase_II
gptkb:TBP |
gptkbp:length |
8 exons
|
gptkbp:locatedOnChromosome |
14q24.3
|
gptkbp:OMIM |
600523
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:orthologInMouse |
Gtf2b
|
gptkbp:orthologInYeast |
SUA7
|
gptkbp:proteinFamily |
TFIIB family
|
gptkbp:significance |
no major disease association known
|
gptkbp:UniProtID |
Q00403
|
gptkbp:bfsParent |
gptkb:TFIIB
|
gptkbp:bfsLayer |
7
|