GTF2B gene

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:TFIIB
TF2B
gptkbp:alternativeSplicing yes
gptkbp:associatedWith transcription regulation
gptkbp:biologicalProcess gene expression
transcription factor activity
gptkbp:cellularComponent gptkb:nucleus
gptkbp:discoveredBy 1992
gptkbp:encodes GTF2B protein
gptkbp:Entrez_Gene_ID 2959
ENSG00000125818
gptkbp:expressedIn various tissues
gptkbp:fullName general transcription factor IIB
gptkbp:function transcription initiation
RNA polymerase II preinitiation complex assembly
gptkbp:HGNC_ID HGNC:4642
https://www.w3.org/2000/01/rdf-schema#label GTF2B gene
gptkbp:interactsWith gptkb:RNA_polymerase_II
gptkb:TBP
gptkbp:length 8 exons
gptkbp:locatedOnChromosome 14q24.3
gptkbp:OMIM 600523
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Gtf2b
gptkbp:orthologInYeast SUA7
gptkbp:proteinFamily TFIIB family
gptkbp:significance no major disease association known
gptkbp:UniProtID Q00403
gptkbp:bfsParent gptkb:TFIIB
gptkbp:bfsLayer 7