GP63 gene

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs leishmanolysin gene
gptkbp:biologicalProcess proteolysis
metalloprotease activity
modulation of host immune response
gptkbp:encodes gptkb:leishmanolysin
gptkbp:expressedIn amastigote stage
promastigote stage
gptkbp:foundIn gptkb:Leishmania_major
gptkbp:function encodes a zinc-dependent metalloprotease
https://www.w3.org/2000/01/rdf-schema#label GP63 gene
gptkbp:locatedOnChromosome chromosome 10 (Leishmania major)
gptkbp:orthologIn gptkb:Leishmania_donovani
gptkb:Leishmania_infantum
gptkb:Leishmania_mexicana
gptkbp:product GP63 protein
gptkbp:roleInPathogenesis facilitates parasite survival in host macrophages
involved in immune evasion
gptkbp:sequence protein-coding
gptkbp:target drug development
vaccine research
gptkbp:bfsParent gptkb:glycoprotein_63
gptkbp:bfsLayer 7