Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
G beta 2
G protein beta subunit 2 |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
signal transduction
congenital heart disease neurodevelopmental disorder with hypotonia and seizures |
| gptkbp:component |
heterotrimeric G protein complex
heterotrimeric G-protein complex |
| gptkbp:encodes |
G protein subunit beta 2
|
| gptkbp:Entrez_Gene_ID |
2783
ENSG00000114388 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit beta-2
|
| gptkbp:function |
GTPase activity
modulates G protein-coupled receptor signaling |
| gptkbp:GOProcess |
signal transduction
|
| gptkbp:HGNC_ID |
4393
|
| https://www.w3.org/2000/01/rdf-schema#label |
GNB2
|
| gptkbp:interactsWith |
gptkb:GNAS
GNAI1 GNAI2 GNAI3 GNAO1 GNG10 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 |
| gptkbp:length |
340 amino acids
|
| gptkbp:locatedOnChromosome |
1p36.3
|
| gptkbp:molecularWeight |
37.4 kDa
|
| gptkbp:mutationAssociatedWith |
neurodevelopmental disorder with hypotonia and seizures
|
| gptkbp:OMIM |
139390
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Gnb2
|
| gptkbp:orthologInZebrafish |
gnb2
|
| gptkbp:PDB |
1TBG
|
| gptkbp:product |
GNB2 protein
|
| gptkbp:RefSeq |
NM_005273
|
| gptkbp:subcellularLocation |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:UniProtID |
P62879
|
| gptkbp:bfsParent |
gptkb:Familial_atrial_fibrillation
gptkb:Gβ_subunit |
| gptkbp:bfsLayer |
7
|