Statements (26)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:Gastric_inhibitory_polypeptide_receptor
gptkb:GIPR |
gptkbp:associatedWith |
gptkb:type_2_diabetes
obesity |
gptkbp:encodedBy |
GIPR gene
|
gptkbp:expressedIn |
central nervous system
adipose tissue pancreatic beta cells |
gptkbp:foundIn |
gptkb:cell_membrane
|
gptkbp:function |
mediates effects of GIP hormone
receptor for gastric inhibitory polypeptide |
https://www.w3.org/2000/01/rdf-schema#label |
GIP receptor protein
|
gptkbp:ligand |
GIP (glucose-dependent insulinotropic polypeptide)
|
gptkbp:locatedOnChromosome |
chromosome 19q13.3
|
gptkbp:memberOf |
gptkb:G_protein-coupled_receptor
|
gptkbp:molecularWeight |
53 kDa
|
gptkbp:OMIM |
137241
|
gptkbp:role |
glucose homeostasis
regulation of insulin secretion |
gptkbp:structure |
7 transmembrane domains
|
gptkbp:type |
activates adenylate cyclase
increases cAMP levels |
gptkbp:UniProtID |
gptkb:P48546
|
gptkbp:bfsParent |
gptkb:GIPR
|
gptkbp:bfsLayer |
7
|