|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
GABA-A receptor subunit beta-2
GABRB2_HUMAN
GBR-B2
|
|
gptkbp:associatedWith
|
Epilepsy
Schizophrenia
Intellectual disability
|
|
gptkbp:database
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:HGNC
gptkb:OMIM
gptkb:UniProt
gptkb:Ensembl
|
|
gptkbp:Entrez_Gene_ID
|
2561
ENSG00000115488
|
|
gptkbp:expressedIn
|
Detected in hippocampus
High in cerebral cortex
|
|
gptkbp:fullName
|
Gamma-aminobutyric acid receptor subunit beta-2
|
|
gptkbp:function
|
Component of the GABA-A receptor, a ligand-gated chloride channel
|
|
gptkbp:gene
|
GABRB2
|
|
gptkbp:hasIsoform
|
2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GBRB2 HUMAN
|
|
gptkbp:length
|
474 amino acids
|
|
gptkbp:locatedOnChromosome
|
5q34
|
|
gptkbp:location
|
gptkb:Cell_membrane
|
|
gptkbp:molecularWeight
|
53 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Gabrb2 (mouse)
Gabrb2 (rat)
|
|
gptkbp:pathway
|
gptkb:GABAergic_synapse
gptkb:Neuroactive_ligand-receptor_interaction
|
|
gptkbp:PDB
|
6HUK
6HUO
6HUP
|
|
gptkbp:postTranslationalModification
|
Phosphorylation
Glycosylation
|
|
gptkbp:RefSeq
|
NP_000808.2
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:subunit
|
Forms pentameric receptor complexes with other GABA-A subunits
|
|
gptkbp:tissue_specificity
|
gptkb:Brain
|
|
gptkbp:transmembraneDomains
|
4
|
|
gptkbp:UniProtID
|
P47870
|
|
gptkbp:bfsParent
|
gptkb:O75899_(GABBR2)
|
|
gptkbp:bfsLayer
|
7
|