GAP domain

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:foundIn gptkb:p120GAP
gptkb:neurofibromin
GTPase-activating proteins
ARHGAP proteins
ASAP proteins
IQGAP proteins
RGS proteins
SynGAP
TBC1D proteins
gptkbp:function stimulates GTPase activity
gptkbp:GO_term GO:0005096
https://www.w3.org/2000/01/rdf-schema#label GAP domain
gptkbp:InterPro IPR001936
gptkbp:involvedIn signal transduction
gptkbp:mechanismOfAction increases hydrolysis of GTP to GDP
gptkbp:proteinFamily PF00616
gptkbp:regulates gptkb:Ras_proteins
Arf proteins
Rab proteins
Ran proteins
Rho proteins
small GTPases
gptkbp:relatedTo cell differentiation
cell proliferation
oncogenesis
gptkbp:structure conserved domain
gptkbp:bfsParent gptkb:RASA1_gene
gptkbp:bfsLayer 7