Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:GAD67
|
| gptkbp:associatedWith |
epilepsy
schizophrenia GABAergic neurotransmission |
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
4.1.1.15
|
| gptkbp:encodedBy |
gptkb:GAD1_gene
|
| gptkbp:Entrez_Gene_ID |
2571
|
| gptkbp:expressedIn |
brain
pancreas |
| gptkbp:fullName |
Glutamate decarboxylase 1
|
| gptkbp:function |
catalyzes the conversion of glutamate to GABA
|
| https://www.w3.org/2000/01/rdf-schema#label |
GAD1 protein
|
| gptkbp:involvedIn |
gptkb:GABA_biosynthetic_process
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_2q31
|
| gptkbp:location |
gptkb:synaptic_vesicle
gptkb:cytoplasm |
| gptkbp:molecularWeight |
67 kDa
|
| gptkbp:mutationAssociatedWith |
can cause neurological disorders
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
mouse GAD1 protein
rat GAD1 protein |
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
gptkb:Q99259
|
| gptkbp:bfsParent |
gptkb:GAD67
|
| gptkbp:bfsLayer |
7
|