G2 checkpoint

GPTKB entity

Statements (21)
Predicate Object
gptkbp:instanceOf cell cycle checkpoint
gptkbp:block mitosis if DNA is damaged
gptkbp:failure_leads_to genomic instability
gptkbp:followedBy gptkb:S_phase
gptkbp:guarantees DNA is fully replicated
DNA is undamaged before mitosis
https://www.w3.org/2000/01/rdf-schema#label G2 checkpoint
gptkbp:importantFor cancer prevention
gptkbp:involves gptkb:p53_protein
gptkb:cyclin-dependent_kinases
ATM protein
ATR protein
Wee1 kinase
checkpoint kinases
Cdc25 phosphatase
gptkbp:partOf cell cycle
gptkbp:precededBy gptkb:M_phase
gptkbp:regulates entry into mitosis
gptkbp:تسمى_أيضا G2/M checkpoint
gptkbp:bfsParent gptkb:Cell_Cycle
gptkbp:bfsLayer 8