Statements (64)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
autoimmune diseases
inflammatory diseases |
| gptkbp:character_traits |
H131 R
R131 H |
| gptkbp:chromosome_location |
1q23.3
|
| gptkbp:expressed_on |
B cells
macrophages monocytes |
| gptkbp:form |
Fc gamma receptor II-A1
Fc gamma receptor II-A2 |
| gptkbp:has_function |
activating B cells
enhancing antibody responses mediating phagocytosis modulating immune responses |
| gptkbp:has_role |
antibody-dependent cellular cytotoxicity
phagocytosis |
| https://www.w3.org/2000/01/rdf-schema#label |
Fc gamma receptor II-A
|
| gptkbp:influences |
vaccine efficacy
antibody responses |
| gptkbp:interacts_with |
Fc gamma receptor I
Fc gamma receptor III |
| gptkbp:involved_in |
cell signaling
immune response allergic reactions pathogen recognition cytokine production immune regulation |
| gptkbp:is_expressed_in |
gptkb:T_cells
myeloid cells dendritic cells natural killer cells |
| gptkbp:is_involved_in |
cell differentiation
cell proliferation signal transduction antigen presentation inflammation pathogen clearance immune tolerance immune cell activation tissue repair viral infections cell migration adaptive immunity bacterial infections tumor immunity tissue homeostasis innate immunity host defense parasitic infections immune surveillance immune cell communication cell-cell interactions immune memory cellular activation |
| gptkbp:is_regulated_by |
transcription factors
cytokines |
| gptkbp:knockouts |
Ig G antibodies
|
| gptkbp:located_in |
immune system
|
| gptkbp:promoter |
gptkb:FCGR2_A
|
| gptkbp:targets |
monoclonal antibodies
therapeutic antibodies |
| gptkbp:bfsParent |
gptkb:FCGR2_A
|
| gptkbp:bfsLayer |
8
|