Familial Adenomatous Polyposis

URI: https://gptkb.org/entity/Familial_Adenomatous_Polyposis
GPTKB entity
Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:genetic_disorder
gptkb:hereditary_cancer_syndrome
gptkbp:abbreviation gptkb:FAP
gptkbp:affectsOrgan gptkb:duodenum
colon
stomach
rectum
gptkbp:associatedWith gptkb:Gardner_syndrome
gptkb:Turcot_syndrome
gptkbp:diagnosedBy genetic testing
colonoscopy
gptkbp:firstDescribed gptkb:Samuel_Wilks
gptkbp:ICD-10_code Q85.8
gptkbp:inheritance autosomal dominant
gptkbp:mainComplication colorectal cancer
desmoid tumors
duodenal cancer
gptkbp:MeSH_ID D010972
gptkbp:mutationAssociatedWith gptkb:APC_gene
gptkbp:OMIM 175100
gptkbp:onset childhood
gptkbp:prevalence 1 in 7,000 to 1 in 22,000 live births
gptkbp:riskFactor family history of FAP
gptkbp:symptom abdominal pain
rectal bleeding
multiple colorectal polyps
gptkbp:synonym gptkb:Adenomatous_polyposis_coli
FAP syndrome
Familial polyposis coli
gptkbp:treatment colectomy
regular surveillance
polypectomy
gptkbp:bfsParent gptkb:FAP
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label Familial Adenomatous Polyposis