Familial Adenomatous Polyposis
GPTKB entity
Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
hereditary cancer syndrome |
| gptkbp:abbreviation |
gptkb:FAP
|
| gptkbp:affectsOrgan |
gptkb:duodenum
colon stomach rectum |
| gptkbp:associatedWith |
gptkb:Gardner_syndrome
gptkb:Turcot_syndrome |
| gptkbp:diagnosedBy |
genetic testing
colonoscopy |
| gptkbp:firstDescribed |
gptkb:Samuel_Wilks
|
| https://www.w3.org/2000/01/rdf-schema#label |
Familial Adenomatous Polyposis
|
| gptkbp:ICD-10_code |
Q85.8
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:mainComplication |
colorectal cancer
desmoid tumors duodenal cancer |
| gptkbp:MeSH_ID |
D010972
|
| gptkbp:mutationAssociatedWith |
gptkb:APC_gene
|
| gptkbp:OMIM |
175100
|
| gptkbp:onset |
childhood
|
| gptkbp:prevalence |
1 in 7,000 to 1 in 22,000 live births
|
| gptkbp:riskFactor |
family history of FAP
|
| gptkbp:symptom |
abdominal pain
rectal bleeding multiple colorectal polyps |
| gptkbp:synonym |
gptkb:Adenomatous_polyposis_coli
FAP syndrome Familial polyposis coli |
| gptkbp:treatment |
colectomy
regular surveillance polypectomy |
| gptkbp:bfsParent |
gptkb:FAP
|
| gptkbp:bfsLayer |
6
|