|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
CD16A
FcgammaRIIIa
Low affinity immunoglobulin gamma Fc region receptor III-A
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
autoimmune diseases
rheumatoid arthritis
|
|
gptkbp:biologicalProcess
|
immune response
phagocytosis
cell activation
immunoglobulin receptor activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:encodes
|
Fc gamma receptor III-A
|
|
gptkbp:Entrez_Gene_ID
|
2214
ENSG00000203747
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
macrophages
|
|
gptkbp:function
|
binds IgG Fc region
mediates antibody-dependent cellular cytotoxicity
|
|
gptkbp:HGNC_ID
|
HGNC:3617
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FCGR3A
|
|
gptkbp:locatedOnChromosome
|
plus
1q23.3
|
|
gptkbp:numberOfExons
|
7
|
|
gptkbp:OMIM
|
146740
|
|
gptkbp:orthologInMouse
|
Fcgr3
|
|
gptkbp:pathway
|
Fc gamma R-mediated phagocytosis
Natural killer cell mediated cytotoxicity
|
|
gptkbp:product
|
CD16a
|
|
gptkbp:UniProtID
|
P08637
|
|
gptkbp:bfsParent
|
gptkb:FCGR_genes
gptkb:chromosome_1q23
|
|
gptkbp:bfsLayer
|
7
|