F1F0-ATP synthase

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alsoKnownAs gptkb:ATP_synthase
gptkbp:ATPProducedPerTurn 3 ATP molecules
gptkbp:composedOf multiple protein subunits
gptkbp:determines X-ray crystallography
cryo-electron microscopy
gptkbp:discoveredBy gptkb:Paul_Boyer
gptkb:John_E._Walker
gptkbp:EC_number 7.1.2.2
gptkbp:F0_sector_function proton channel
gptkbp:F1_sector_function catalytic ATP synthesis
gptkbp:firstDescribed 1960s
gptkbp:foundIn gptkb:bacterial_plasma_membrane
gptkb:chloroplast_thylakoid_membrane
mitochondrial inner membrane
gptkbp:function synthesizes ATP from ADP and inorganic phosphate
gptkbp:gene gptkb:ATP5F1D
gptkb:ATP5F1E
gptkb:ATP5F1A
gptkb:ATP5F1B
gptkb:ATP5F1C
gptkb:ATP5MC1
gptkb:ATP5MC2
gptkb:ATP5MC3
gptkb:ATP5ME
gptkb:ATP5MF
gptkb:ATP5MG
gptkb:ATP5PB
gptkb:ATP5PD
gptkb:ATP5PF
https://www.w3.org/2000/01/rdf-schema#label F1F0-ATP synthase
gptkbp:inhibitedBy gptkb:oligomycin
gptkbp:involvedIn oxidative phosphorylation
photophosphorylation
gptkbp:mechanismOfAction rotary catalysis
gptkbp:molecularWeight ~600 kDa
gptkbp:NobelPrizeYear 1997 Chemistry
gptkbp:notableDriver proton gradient
gptkbp:orthologIn V-type ATPase
A-type ATPase
gptkbp:powerSource proton motive force to chemical energy
gptkbp:presentIn prokaryotes
eukaryotes
gptkbp:requires cellular energy production
gptkbp:rotationPeriod up to 130 revolutions per second
gptkbp:subunit gptkb:F1_sector
F0 sector
gptkbp:target antibiotics
antifungal agents
gptkbp:bfsParent gptkb:CHEBI:15765
gptkbp:bfsLayer 7