Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:cofactor |
Mg2+
|
| gptkbp:discoveredBy |
Richard L. Sinsheimer
|
| gptkbp:discoveredIn |
1966
|
| gptkbp:EC_number |
3.1.11.2
|
| gptkbp:foundIn |
gptkb:Bacteria
|
| gptkbp:function |
exhibits exonuclease activity
removes nucleotides from 3' ends of DNA exhibits endonuclease activity on apurinic/apyrimidinic sites |
| gptkbp:gene |
xthA
|
| https://www.w3.org/2000/01/rdf-schema#label |
Exonuclease III
|
| gptkbp:inhibitedBy |
gptkb:EDTA
|
| gptkbp:molecularWeight |
28 kDa
|
| gptkbp:notableFor |
does not degrade single-stranded DNA
has RNase H activity removes mononucleotides from 3' ends |
| gptkbp:optimum_pH |
7.5
|
| gptkbp:substrate |
double-stranded DNA
apurinic/apyrimidinic DNA |
| gptkbp:used_in |
molecular biology
|
| gptkbp:usedFor |
creating unidirectional deletions in DNA
|
| gptkbp:bfsParent |
gptkb:DNA_exonuclease
|
| gptkbp:bfsLayer |
7
|