ExoS

GPTKB entity

Statements (19)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:discoveredIn 1990s
gptkbp:domain C-terminal ADP-ribosyltransferase domain
N-terminal GAP domain
gptkbp:effect disrupts host cell cytoskeleton
induces cell death
inhibits phagocytosis
gptkbp:foundIn gptkb:Pseudomonas_aeruginosa
gptkbp:function GTPase-activating protein activity
ADP-ribosyltransferase activity
gptkbp:gene gptkb:exoS
https://www.w3.org/2000/01/rdf-schema#label ExoS
gptkbp:molecularWeight ~49 kDa
gptkbp:role bacterial virulence
gptkbp:secretes gptkb:Type_III_secretion_system
gptkbp:structure bifunctional enzyme
gptkbp:target host cell proteins
gptkbp:bfsParent gptkb:PA14
gptkbp:bfsLayer 7