Ergotaminum

URI: https://gptkb.org/entity/Ergotaminum

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:drug alkaloid
gptkbp:affiliatedWith	gptkb:ergot_alkaloids
gptkbp:ATCCode	N02CA02
gptkbp:CASNumber	113-15-5
gptkbp:chemicalFormula	C33H35N5O5
gptkbp:contraindication	pregnancy coronary artery disease peripheral vascular disease
gptkbp:derivedFrom	gptkb:Claviceps_purpurea
gptkbp:discoveredBy	gptkb:Arthur_Stoll
gptkbp:discoveredIn	1918
gptkbp:eliminationHalfLife	2 hours
gptkbp:excretion	urine bile
https://www.w3.org/2000/01/rdf-schema#label	Ergotaminum
gptkbp:IUPACName	(6aR,9R)-N-[(2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-methyl-2,3,4,5,6,10a,10b-octahydro-1H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-9-yl]methyl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
gptkbp:legalStatus	prescription only
gptkbp:meltingPoint	210°C
gptkbp:MeSH_ID	D004885
gptkbp:metabolism	liver
gptkbp:molecularWeight	581.67 g/mol
gptkbp:pregnancyCategory	gptkb:X_(US)
gptkbp:PubChem_CID	8223 DB00696 CHEMBL1200698
gptkbp:routeOfAdministration	oral sublingual rectal
gptkbp:sideEffect	nausea vomiting vasoconstriction
gptkbp:synonym	gptkb:Ergotamine Ergotamin
gptkbp:UNII	8Y164V895Y
gptkbp:usedFor	migraine treatment
gptkbp:bfsParent	gptkb:Ergotamine
gptkbp:bfsLayer	7