Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:compatibleWith |
BCG vaccine strains
|
| gptkbp:encodedBy |
esxA gene
|
| gptkbp:foundIn |
gptkb:Mycobacterium_bovis
gptkb:Mycobacterium_tuberculosis |
| gptkbp:fullName |
Early Secreted Antigenic Target 6 kDa
|
| gptkbp:function |
virulence factor
T-cell antigen |
| https://www.w3.org/2000/01/rdf-schema#label |
ESAT-6
|
| gptkbp:locatedOnChromosome |
Rv3875 (M. tuberculosis H37Rv genome)
|
| gptkbp:molecularWeight |
6 kDa
|
| gptkbp:recognizedBy |
human immune system
|
| gptkbp:role |
host-pathogen interaction
granuloma formation |
| gptkbp:secretionSystem |
ESX-1
|
| gptkbp:sequence |
95 amino acids
|
| gptkbp:structure |
forms complex with CFP-10
|
| gptkbp:usedAs |
biomarker for tuberculosis infection
|
| gptkbp:usedIn |
tuberculosis diagnosis
interferon-gamma release assays |
| gptkbp:bfsParent |
gptkb:Mycobacterium_tuberculosis_subsp._tuberculosis
|
| gptkbp:bfsLayer |
7
|