Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
gptkb:Hu_proteins
|
gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases neural development |
gptkbp:binds |
AU-rich elements in mRNA
|
gptkbp:contains |
RNA recognition motif (RRM)
|
gptkbp:expressedIn |
neurons
other tissues (HuR) |
gptkbp:foundIn |
animals
|
gptkbp:function |
RNA-binding
regulation of mRNA translation regulation of mRNA stability regulation of mRNA splicing |
https://www.w3.org/2000/01/rdf-schema#label |
ELAV-like proteins
|
gptkbp:member |
HuB
HuC HuD HuR |
gptkbp:namedAfter |
embryonic lethal abnormal vision (elav) gene in Drosophila
|
gptkbp:orthologIn |
Drosophila ELAV protein
human ELAVL1 (HuR) human ELAVL2 (HuB) human ELAVL3 (HuC) human ELAVL4 (HuD) |
gptkbp:regulates |
gene expression post-transcriptionally
|
gptkbp:bfsParent |
gptkb:RRM_domain
|
gptkbp:bfsLayer |
7
|