ELAV-like proteins

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:Hu_proteins
gptkbp:associatedWith gptkb:cancer
neurodegenerative diseases
neural development
gptkbp:binds AU-rich elements in mRNA
gptkbp:contains RNA recognition motif (RRM)
gptkbp:expressedIn neurons
other tissues (HuR)
gptkbp:foundIn animals
gptkbp:function RNA-binding
regulation of mRNA translation
regulation of mRNA stability
regulation of mRNA splicing
https://www.w3.org/2000/01/rdf-schema#label ELAV-like proteins
gptkbp:member HuB
HuC
HuD
HuR
gptkbp:namedAfter embryonic lethal abnormal vision (elav) gene in Drosophila
gptkbp:orthologIn Drosophila ELAV protein
human ELAVL1 (HuR)
human ELAVL2 (HuB)
human ELAVL3 (HuC)
human ELAVL4 (HuD)
gptkbp:regulates gene expression post-transcriptionally
gptkbp:bfsParent gptkb:RRM_domain
gptkbp:bfsLayer 7