EF-G

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Translocase
gptkbp:binds gptkb:GTP
ribosome
gptkbp:discoveredBy gptkb:Masayasu_Nomura
gptkbp:discoveredIn 1960s
gptkbp:domain five domains (G, II, III, IV, V)
gptkbp:fullName Elongation factor G
gptkbp:function catalyzes translocation step in protein synthesis
gptkbp:gene fusA
https://www.w3.org/2000/01/rdf-schema#label EF-G
gptkbp:inhibitedBy fusidic acid
gptkbp:location gptkb:cytoplasm
gptkbp:mechanismOfAction GTP hydrolysis-driven conformational change
gptkbp:molecularWeight 77 kDa
gptkbp:organism gptkb:Bacteria
gptkbp:orthologIn eEF2 (in eukaryotes)
gptkbp:PDB 4V5F
gptkbp:requires translation elongation
gptkbp:structure guanine nucleotide exchange factor
gptkbp:UniProtID P0A6M8 (E. coli)
gptkbp:bfsParent gptkb:Elongation_factor
gptkbp:bfsLayer 7