TAF15
E561107
TAF15 is an RNA-binding protein and transcription factor associated with gene regulation and implicated in certain cancers and neurodegenerative diseases.
All labels observed (1)
| Label | Occurrences |
|---|---|
| TAF15 canonical | 2 |
How this entity was disambiguated
This entity first appeared as the object of triple T6004989 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: TAF15 Context triple: [FUS, interactsWith, TAF15]
-
A.
TAF
TAF is the acronym for Technology Academy Finland, an independent foundation best known for awarding the international Millennium Technology Prize and promoting innovations that improve quality of life.
-
B.
Flight 15P
Flight 15P was the historic 2004 suborbital test flight of SpaceShipOne that became the first privately funded human spaceflight.
-
C.
UA175
UA175 was the IATA flight number for United Airlines Flight 175, the passenger flight hijacked and crashed into the South Tower of the World Trade Center during the September 11, 2001 terrorist attacks.
-
D.
C-1FTB
The C-1FTB is a specialized variant of the Kawasaki C-1 military transport aircraft, modified primarily for flight test and evaluation purposes.
-
E.
Terminal 1E
Terminal 1E is a passenger terminal facility at Jomo Kenyatta International Airport in Nairobi, Kenya, serving international air travelers.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: TAF15 Target entity description: TAF15 is an RNA-binding protein and transcription factor associated with gene regulation and implicated in certain cancers and neurodegenerative diseases.
-
A.
TAF
TAF is the acronym for Technology Academy Finland, an independent foundation best known for awarding the international Millennium Technology Prize and promoting innovations that improve quality of life.
-
B.
Flight 15P
Flight 15P was the historic 2004 suborbital test flight of SpaceShipOne that became the first privately funded human spaceflight.
-
C.
UA175
UA175 was the IATA flight number for United Airlines Flight 175, the passenger flight hijacked and crashed into the South Tower of the World Trade Center during the September 11, 2001 terrorist attacks.
-
D.
C-1FTB
The C-1FTB is a specialized variant of the Kawasaki C-1 military transport aircraft, modified primarily for flight test and evaluation purposes.
-
E.
Terminal 1E
Terminal 1E is a passenger terminal facility at Jomo Kenyatta International Airport in Nairobi, Kenya, serving international air travelers.
- F. None of above. chosen
Statements (49)
| Predicate | Object |
|---|---|
| instanceOf |
RNA-binding protein
ⓘ
gene regulatory protein ⓘ protein ⓘ transcription factor ⓘ |
| aggregationLinkedTo | neurodegeneration ⓘ |
| alsoKnownAs |
RBP56
ⓘ
TAFII68 ⓘ |
| associatedWith |
acute leukemia
ⓘ
amyotrophic lateral sclerosis ⓘ cancer ⓘ frontotemporal dementia ⓘ neurodegenerative disease ⓘ sarcoma ⓘ |
| bindsMolecule |
DNA
ⓘ
RNA ⓘ single-stranded RNA ⓘ |
| canAggregate | yes ⓘ |
| conservedIn | vertebrates ⓘ |
| encodedBy | TAF15 gene ⓘ |
| formsFusionWith |
CIZ/NMP4
ⓘ
EWSR1-related partners ⓘ MLL ⓘ NR4A3 ⓘ |
| fullName | TATA-box binding protein associated factor 15 ⓘ |
| hasDomain |
RGG-rich region
ⓘ
RNA recognition motif ⓘ low-complexity prion-like domain ⓘ |
| hasMolecularFunction |
DNA binding
ⓘ
RNA binding ⓘ RNA splicing factor activity ⓘ transcription coactivator activity ⓘ |
| implicatedIn |
aberrant RNA metabolism
ⓘ
aberrant transcriptional activation ⓘ oncogenic gene fusions ⓘ |
| interactsWith |
RNA polymerase II transcription machinery
ⓘ
TATA-binding protein associated factors ⓘ |
| locatedIn |
cytoplasm
ⓘ
nucleus ⓘ |
| memberOf | FET protein family ⓘ |
| orthologIn | Homo sapiens ⓘ |
| participatesIn |
RNA processing
ⓘ
gene expression regulation ⓘ mRNA splicing ⓘ mRNA stability regulation ⓘ transcription regulation ⓘ |
| postTranslationalModification |
arginine methylation
ⓘ
phosphorylation ⓘ |
| subcellularLocalization |
nuclear speckles
ⓘ
stress granules ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: TAF15 Description of subject: TAF15 is an RNA-binding protein and transcription factor associated with gene regulation and implicated in certain cancers and neurodegenerative diseases.
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.