TATA-binding protein associated factors
E1551053
UNEXPLORED
TATA-binding protein associated factors (TAFs) are a group of proteins that form part of the TFIID complex, playing a central role in recognizing promoter DNA and regulating transcription initiation by RNA polymerase II.
All labels observed (1)
| Label | Occurrences |
|---|---|
| TATA-binding protein associated factors canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22693465 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: TATA-binding protein associated factors Context triple: [TAF15, interactsWith, TATA-binding protein associated factors]
-
A.
CTCF
CTCF is a state prison facility in Colorado that houses incarcerated individuals under the jurisdiction of the Colorado Department of Corrections.
-
B.
MAFA transcription factor
MAFA transcription factor is a beta cell–specific transcription factor that plays a key role in regulating insulin gene expression and pancreatic islet function.
-
C.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
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D.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
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E.
FOXA2 transcription factor
FOXA2 transcription factor is a forkhead box transcription factor that plays a key role in regulating genes involved in pancreatic beta-cell function, glucose metabolism, and endoderm development.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: TATA-binding protein associated factors Target entity description: TATA-binding protein associated factors (TAFs) are a group of proteins that form part of the TFIID complex, playing a central role in recognizing promoter DNA and regulating transcription initiation by RNA polymerase II.
-
A.
CTCF
CTCF is a state prison facility in Colorado that houses incarcerated individuals under the jurisdiction of the Colorado Department of Corrections.
-
B.
MAFA transcription factor
MAFA transcription factor is a beta cell–specific transcription factor that plays a key role in regulating insulin gene expression and pancreatic islet function.
-
C.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
D.
RNA polymerase II
RNA polymerase II is the eukaryotic enzyme complex responsible for transcribing DNA into messenger RNA and many non-coding RNAs, playing a central role in gene expression.
-
E.
FOXA2 transcription factor
FOXA2 transcription factor is a forkhead box transcription factor that plays a key role in regulating genes involved in pancreatic beta-cell function, glucose metabolism, and endoderm development.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.