NR4A3
E1551049
UNEXPLORED
NR4A3 is a nuclear receptor transcription factor involved in regulating gene expression linked to cell growth, differentiation, and oncogenic fusion events in certain cancers.
All labels observed (1)
| Label | Occurrences |
|---|---|
| NR4A3 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22693451 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: NR4A3 Context triple: [TAF15, formsFusionWith, NR4A3]
-
A.
NEUROD1 transcription factor
NEUROD1 transcription factor is a basic helix-loop-helix (bHLH) transcription factor crucial for neuronal differentiation and pancreatic beta-cell development, where it helps control insulin gene expression.
-
B.
Oct3/4
Oct3/4 (also known as POU5F1) is a key transcription factor that maintains pluripotency and self-renewal in embryonic stem cells and is widely used in cellular reprogramming.
-
C.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
-
D.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
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E.
GRIN3B
GRIN3B is a human gene that encodes the GluN3B subunit of NMDA-type glutamate receptors involved in excitatory neurotransmission and synaptic plasticity in the central nervous system.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: NR4A3 Target entity description: NR4A3 is a nuclear receptor transcription factor involved in regulating gene expression linked to cell growth, differentiation, and oncogenic fusion events in certain cancers.
-
A.
NEUROD1 transcription factor
NEUROD1 transcription factor is a basic helix-loop-helix (bHLH) transcription factor crucial for neuronal differentiation and pancreatic beta-cell development, where it helps control insulin gene expression.
-
B.
Oct3/4
Oct3/4 (also known as POU5F1) is a key transcription factor that maintains pluripotency and self-renewal in embryonic stem cells and is widely used in cellular reprogramming.
-
C.
Sox2
Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
-
D.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
E.
GRIN3B
GRIN3B is a human gene that encodes the GluN3B subunit of NMDA-type glutamate receptors involved in excitatory neurotransmission and synaptic plasticity in the central nervous system.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.