Zoloft
E474931
Zoloft is a widely prescribed antidepressant medication (sertraline) in the selective serotonin reuptake inhibitor (SSRI) class, commonly used to treat depression, anxiety disorders, and related conditions.
All labels observed (2)
| Label | Occurrences |
|---|---|
| sertraline | 4 |
| Zoloft canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4850379 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Zoloft Context triple: [Pfizer, developed, Zoloft]
-
A.
Prozac
Prozac is a widely prescribed antidepressant medication (fluoxetine) used to treat major depressive disorder, anxiety disorders, and certain other mental health conditions.
-
B.
Cymbalta
Cymbalta is a prescription antidepressant medication (duloxetine) commonly used to treat major depressive disorder, generalized anxiety disorder, and certain types of chronic pain.
-
C.
Lamotrek
Lamotrek is a small atoll in the Federated States of Micronesia known for its traditional seafaring culture and navigational expertise.
-
D.
Ambien
Ambien is a widely prescribed sedative-hypnotic medication (generic name zolpidem) used short-term to treat insomnia by helping people fall asleep more quickly.
-
E.
Anpezan
Anpezan is a regional dialect of the Ladin language spoken in parts of the Dolomite area of northern Italy.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Zoloft Target entity description: Zoloft is a widely prescribed antidepressant medication (sertraline) in the selective serotonin reuptake inhibitor (SSRI) class, commonly used to treat depression, anxiety disorders, and related conditions.
-
A.
Prozac
Prozac is a widely prescribed antidepressant medication (fluoxetine) used to treat major depressive disorder, anxiety disorders, and certain other mental health conditions.
-
B.
Cymbalta
Cymbalta is a prescription antidepressant medication (duloxetine) commonly used to treat major depressive disorder, generalized anxiety disorder, and certain types of chronic pain.
-
C.
Lamotrek
Lamotrek is a small atoll in the Federated States of Micronesia known for its traditional seafaring culture and navigational expertise.
-
D.
Ambien
Ambien is a widely prescribed sedative-hypnotic medication (generic name zolpidem) used short-term to treat insomnia by helping people fall asleep more quickly.
-
E.
Anpezan
Anpezan is a regional dialect of the Ladin language spoken in parts of the Dolomite area of northern Italy.
- F. None of above. chosen
Statements (57)
| Predicate | Object |
|---|---|
| instanceOf |
antidepressant
ⓘ
brand name ⓘ pharmaceutical drug ⓘ selective serotonin reuptake inhibitor ⓘ |
| affects | serotonin reuptake ⓘ |
| hasATCCode | N06AB06 ⓘ |
| hasBlackBoxWarning | increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults ⓘ |
| hasCommonSideEffect |
decreased libido
ⓘ
diarrhea ⓘ dry mouth ⓘ ejaculatory delay ⓘ headache ⓘ insomnia ⓘ nausea ⓘ sexual dysfunction ⓘ somnolence ⓘ |
| hasCommonStartingDose_mgPerDay |
25
ⓘ
50 ⓘ |
| hasDosageForm |
oral concentrate
ⓘ
tablet ⓘ |
| hasDrugClass | SSRI ⓘ |
| hasEliminationHalfLife_hours | 26 ⓘ |
| hasFDAApprovalYear | 1991 ⓘ |
| hasFullEffectTime_weeks | 4–6 ⓘ |
| hasGenericName |
sertraline
ⓘ
linked to:
Zoloft
|
| hasLegalStatus_UK | POM ⓘ |
| hasLegalStatus_US | Rx-only ⓘ |
| hasMaximumTypicalDose_mgPerDay | 200 ⓘ |
| hasMechanismOfAction | inhibition of serotonin transporter ⓘ |
| hasOnsetOfAction_weeks | 1–2 ⓘ |
| hasPregnancyCategory_US | C ⓘ |
| hasProteinBinding_percent | 98 ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| hasSeriousAdverseEffect |
QT prolongation
ⓘ
hyponatremia ⓘ serotonin syndrome ⓘ suicidal ideation ⓘ |
| isAdministeredOnce | daily ⓘ |
| isContraindicatedWith |
MAO inhibitors
ⓘ
pimozide ⓘ |
| isManufacturedBy | Pfizer ⓘ |
| isMetabolizedBy |
CYP2B6
ⓘ
CYP2C19 ⓘ CYP2D6 ⓘ CYP3A4 ⓘ |
| isPrescriptionStatus_EU | prescription only ⓘ |
| isPrescriptionStatus_US | prescription only ⓘ |
| isTakenWithOrWithout | food ⓘ |
| isUsedFor |
generalized anxiety disorder
ⓘ
major depressive disorder ⓘ obsessive-compulsive disorder ⓘ panic disorder ⓘ post-traumatic stress disorder ⓘ premenstrual dysphoric disorder ⓘ social anxiety disorder ⓘ |
| tradeNameOf |
sertraline
ⓘ
linked to:
Zoloft
|
| wasApprovedBy |
U.S. Food and Drug Administration
ⓘ
linked to:
Food and Drug Administration
|
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Zoloft Description of subject: Zoloft is a widely prescribed antidepressant medication (sertraline) in the selective serotonin reuptake inhibitor (SSRI) class, commonly used to treat depression, anxiety disorders, and related conditions.
Referenced by (5)
Full triples — surface form annotated when it differs from this entity's canonical label.
linked to: Zoloft
linked to: Zoloft
linked to: Zoloft
linked to: Zoloft