|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:DNM1
Dynamin I
|
|
gptkbp:associatedWith
|
epileptic encephalopathy (when mutated)
|
|
gptkbp:discoveredBy
|
gptkb:Sandra_L._Schmid
|
|
gptkbp:discoveredIn
|
1989
|
|
gptkbp:domain
|
GTPase domain
GTPase effector domain
proline-rich domain
Pleckstrin homology domain
|
|
gptkbp:encodedBy
|
gptkb:DNM1_gene
|
|
gptkbp:expressedIn
|
neurons
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
GTPase activity
membrane fission
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dynamin 1
|
|
gptkbp:interactsWith
|
gptkb:amphiphysin
gptkb:endophilin
synaptojanin
|
|
gptkbp:involvedIn
|
synaptic vesicle endocytosis
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_9q34.11
|
|
gptkbp:location
|
gptkb:cytoplasm
presynaptic terminal
|
|
gptkbp:molecularWeight
|
~100 kDa
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:participatedIn
|
clathrin-mediated endocytosis
|
|
gptkbp:PDB
|
3SNH
|
|
gptkbp:regulates
|
phosphorylation-dependent
|
|
gptkbp:UniProtID
|
gptkb:Q05193
|
|
gptkbp:bfsParent
|
gptkb:Dynamin_family
|
|
gptkbp:bfsLayer
|
7
|