Dihydrotestosterone receptor
GPTKB entity
Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
nuclear receptor |
gptkbp:activatedBy |
gptkb:androgens
|
gptkbp:binds |
gptkb:dihydrotestosterone
testosterone |
gptkbp:biologicalProcess |
DNA binding
steroid hormone receptor activity |
gptkbp:encodedBy |
gptkb:AR_gene
|
gptkbp:foundIn |
humans
mammals |
gptkbp:function |
regulates gene expression
|
gptkbp:gene |
AR
|
https://www.w3.org/2000/01/rdf-schema#label |
Dihydrotestosterone receptor
|
gptkbp:locatedOnChromosome |
gptkb:Xq11-12
|
gptkbp:location |
gptkb:cytoplasm
cell nucleus |
gptkbp:mutationAssociatedWith |
gptkb:androgen_insensitivity_syndrome
prostate cancer |
gptkbp:otherName |
gptkb:androgen_receptor
|
gptkbp:regulates |
transcription of target genes
|
gptkbp:role |
male sexual development
hair growth regulation prostate development |
gptkbp:structure |
contains DNA-binding domain
contains ligand-binding domain |
gptkbp:UniProtID |
P10275
|
gptkbp:bfsParent |
gptkb:P06493
|
gptkbp:bfsLayer |
6
|