|
gptkbp:instanceOf
|
gptkb:drug
alkaloid
|
|
gptkbp:ATCCode
|
N02CA01
|
|
gptkbp:brand
|
D.H.E. 45
Migranal
|
|
gptkbp:CASNumber
|
511-12-6
|
|
gptkbp:category
|
vasoconstrictor
serotonin receptor agonist
antimigraine agent
|
|
gptkbp:chemicalFormula
|
C33H37N5O5
|
|
gptkbp:contraindication
|
pregnancy
coronary artery disease
uncontrolled hypertension
|
|
gptkbp:discoveredBy
|
gptkb:Sandoz
|
|
gptkbp:discoveredIn
|
1943
|
|
gptkbp:eliminationHalfLife
|
10 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dihydroergotamine
|
|
gptkbp:KEGGID
|
D07713
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
vasoconstriction
|
|
gptkbp:MedlinePlusID
|
a601203
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
583.68 g/mol
|
|
gptkbp:pregnancyCategory
|
gptkb:X_(US)
|
|
gptkbp:PubChem_CID
|
CHEMBL1201207
441320
DB00323
|
|
gptkbp:relatedTo
|
gptkb:ergotamine
|
|
gptkbp:routeOfAdministration
|
intramuscular
subcutaneous
intravenous
intranasal
|
|
gptkbp:sideEffect
|
nausea
vomiting
dizziness
hypertension
|
|
gptkbp:UNII
|
8Y164V895Y
|
|
gptkbp:usedFor
|
migraine treatment
cluster headache treatment
|
|
gptkbp:bfsParent
|
gptkb:DHE
|
|
gptkbp:bfsLayer
|
6
|