|
gptkbp:instanceOf
|
gptkb:drug
antitussive
|
|
gptkbp:abusePotential
|
yes
|
|
gptkbp:activeIngredientOf
|
cough suppressant medications
|
|
gptkbp:approvedBy
|
1958 (US)
|
|
gptkbp:ATCCode
|
R05DA09
|
|
gptkbp:brand
|
gptkb:Delsym
gptkb:NyQuil
gptkb:Robitussin
|
|
gptkbp:broadcastOn
|
unscheduled (US, most states)
|
|
gptkbp:CASNumber
|
6700-34-1
|
|
gptkbp:chemicalFormula
|
C18H26BrNO
|
|
gptkbp:color
|
white
|
|
gptkbp:compatibleWith
|
pain relief
bacterial infections
|
|
gptkbp:contraindication
|
MAOI use
|
|
gptkbp:discoveredIn
|
1950s
|
|
gptkbp:drugClass
|
opioid
|
|
gptkbp:eliminationHalfLife
|
3-6 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:flavor
|
bitter
|
|
gptkbp:foundIn
|
over-the-counter cough and cold remedies
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dextromethorphan HBr
|
|
gptkbp:interactsWith
|
gptkb:SSRIs
CYP2D6 inhibitors
MAOIs
|
|
gptkbp:legalStatus
|
OTC (over-the-counter) in many countries
|
|
gptkbp:mechanismOfAction
|
NMDA receptor antagonist
sigma-1 receptor agonist
|
|
gptkbp:metabolism
|
gptkb:dextrorphan
liver
|
|
gptkbp:overdoseSymptoms
|
hypertension
dissociation
tachycardia
hallucinations
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sells
|
gptkb:sugar
gptkb:tablet
capsule
lozenge
|
|
gptkbp:sideEffect
|
nausea
vomiting
dizziness
drowsiness
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:usedFor
|
cough
|
|
gptkbp:bfsParent
|
gptkb:Vicks_Formula_44
|
|
gptkbp:bfsLayer
|
7
|