|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvalYear
|
1997
|
|
gptkbp:ATCCode
|
J01DD15
|
|
gptkbp:bioavailability
|
21%
|
|
gptkbp:CASNumber
|
91832-40-5
|
|
gptkbp:color
|
white to slightly yellowish powder
|
|
gptkbp:contraindication
|
patients with known allergy to cephalosporins
|
|
gptkbp:drugClass
|
gptkb:antibiotic
gptkb:cephalosporin
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:generation
|
gptkb:cephalosporin
|
|
gptkbp:halfLife
|
1.7 hours
|
|
gptkbp:hasChEMBL
|
CHEMBL1173
|
|
gptkbp:hasInChIKey
|
QYURTLLQXLPFHB-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
C14H13N5O5S2
|
|
gptkbp:hasSMILES
|
COC1=CC=C(C=C1)C2=NC3=C(C(=O)N2)N(C(=O)CS3)C(=O)O
|
|
gptkbp:hasUNII
|
9Q1OE8U6S5
|
|
gptkbp:indication
|
gptkb:sinusitis
gptkb:otitis_media
bronchitis
tonsillitis
treatment of bacterial infections
pharyngitis
community-acquired pneumonia
skin and skin structure infections
|
|
gptkbp:legalStatus
|
expired
prescription only
|
|
gptkbp:manufacturer
|
gptkb:Abbott_Laboratories
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:meltingPoint
|
>200°C
|
|
gptkbp:metabolism
|
not significantly metabolized
|
|
gptkbp:molecularWeight
|
395.414
|
|
gptkbp:name
|
Cefdinir
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:proteinBinding
|
60-70%
|
|
gptkbp:PubChem_CID
|
gptkb:DB04868
3494
606378
D00251
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
diarrhea
headache
rash
vaginal moniliasis
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:status
|
true
|
|
gptkbp:synonym
|
Cefdinirum
Omnicef
|
|
gptkbp:target
|
penicillin-binding proteins
|
|
gptkbp:bfsParent
|
gptkb:nilotinib
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DB04868
|