DB04868

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:approvalYear 1997
gptkbp:ATCCode J01DD15
gptkbp:bioavailability 21%
gptkbp:CASNumber 91832-40-5
gptkbp:color white to slightly yellowish powder
gptkbp:contraindication patients with known allergy to cephalosporins
gptkbp:drugClass gptkb:antibiotic
cephalosporin
gptkbp:excretion renal
gptkbp:generation cephalosporin
gptkbp:halfLife 1.7 hours
gptkbp:hasChEMBL CHEMBL1173
gptkbp:hasInChIKey QYURTLLQXLPFHB-UHFFFAOYSA-N
gptkbp:hasMolecularFormula C14H13N5O5S2
gptkbp:hasSMILES COC1=CC=C(C=C1)C2=NC3=C(C(=O)N2)N(C(=O)CS3)C(=O)O
gptkbp:hasUNII 9Q1OE8U6S5
https://www.w3.org/2000/01/rdf-schema#label DB04868
gptkbp:indication gptkb:sinusitis
bronchitis
tonsillitis
treatment of bacterial infections
otitis media
pharyngitis
community-acquired pneumonia
skin and skin structure infections
gptkbp:legalStatus expired
prescription only
gptkbp:manufacturer gptkb:Abbott_Laboratories
gptkbp:mechanismOfAction inhibits bacterial cell wall synthesis
gptkbp:meltingPoint >200°C
gptkbp:metabolism not significantly metabolized
gptkbp:molecularWeight 395.414
gptkbp:name Cefdinir
gptkbp:pregnancyCategory B (US)
gptkbp:proteinBinding 60-70%
gptkbp:PubChem_CID gptkb:DB04868
3494
606378
D00251
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
diarrhea
headache
rash
vaginal moniliasis
gptkbp:solubility slightly soluble in water
gptkbp:status true
gptkbp:synonym Cefdinirum
Omnicef
gptkbp:target penicillin-binding proteins
gptkbp:bfsParent gptkb:nilotinib
gptkbp:bfsLayer 6