|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:ATCCode
|
gptkb:L01XC06
|
|
gptkbp:brand
|
gptkb:Erbitux
|
|
gptkbp:CASNumber
|
gptkb:205923-56-4
|
|
gptkbp:developer
|
gptkb:ImClone_Systems
gptkb:Merck_KGaA
gptkb:Bristol-Myers_Squibb
|
|
gptkbp:drugClass
|
gptkb:monoclonal_antibody
antineoplastic agent
|
|
gptkbp:halfLife
|
112 hours
|
|
gptkbp:hasDrugBankURL
|
https://go.drugbank.com/drugs/DB00041
|
|
gptkbp:hasMolecularFormula
|
C6488H10042N1724O2023S36
|
|
gptkbp:hasSMILES
|
not applicable (protein)
|
|
gptkbp:hasUNII
|
PQX0D8J21J
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DB00041
|
|
gptkbp:indication
|
colorectal cancer
head and neck cancer
|
|
gptkbp:isChimericAntibody
|
true
|
|
gptkbp:isMonoclonalAntibody
|
true
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
EGFR inhibitor
|
|
gptkbp:molecularWeight
|
145782.7
|
|
gptkbp:name
|
Cetuximab
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:proteinBinding
|
not applicable
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
hypomagnesemia
infusion reaction
acneiform rash
|
|
gptkbp:status
|
true
|
|
gptkbp:synonym
|
C225
IMC-C225
|
|
gptkbp:target
|
gptkb:Epidermal_growth_factor_receptor
|
|
gptkbp:bfsParent
|
gptkb:Proleukin
|
|
gptkbp:bfsLayer
|
6
|