Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:brand
gptkb:drug |
| gptkbp:activeIngredient |
gptkb:cyclophosphamide
|
| gptkbp:approvedBy |
1959
|
| gptkbp:ATCCode |
L01AA01
|
| gptkbp:contraindication |
pregnancy
severe bone marrow suppression |
| gptkbp:eliminationHalfLife |
3-12 hours
|
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cytoxan
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:manufacturer |
gptkb:Bristol-Myers_Squibb
|
| gptkbp:mechanismOfAction |
antineoplastic agent
DNA crosslinking |
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
D
|
| gptkbp:riskFactor |
immunosuppression
secondary malignancies |
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
nausea
vomiting hair loss infertility bone marrow suppression hemorrhagic cystitis |
| gptkbp:usedFor |
gptkb:cancer
immunosuppression autoimmune diseases nephrotic syndrome |
| gptkbp:bfsParent |
gptkb:cyclophosphamide
|
| gptkbp:bfsLayer |
6
|