Cytidine triphosphate synthase

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName CTP synthetase
CTPS
gptkbp:catalyzes conversion of UTP to CTP
gptkbp:cofactor gptkb:ATP
gptkb:glutamine
gptkbp:EC_number 6.3.4.2
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:gene CTPS1
CTPS2
gptkbp:GO_term GO:0003883
https://www.w3.org/2000/01/rdf-schema#label Cytidine triphosphate synthase
gptkbp:inhibitedBy DON (6-diazo-5-oxo-L-norleucine)
cyclopentenyl cytosine
gptkbp:involves pyrimidine biosynthesis
gptkbp:locatedIn gptkb:cytoplasm
gptkbp:PDB_ID_(structure) 2V4U
2W7T
gptkbp:product gptkb:ADP
phosphate
glutamate
cytidine triphosphate (CTP)
gptkbp:regulates feedback inhibition by CTP
gptkbp:structure homotetramer
gptkbp:substrate gptkb:ATP
gptkb:glutamine
uridine triphosphate (UTP)
gptkbp:UniProt_ID_(human_CTPS1) P17812
gptkbp:UniProt_ID_(human_CTPS2) O43543
gptkbp:bfsParent gptkb:URA7
gptkbp:bfsLayer 7