Cyclin-dependent kinase

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy cyclin binding
gptkbp:alternativeName gptkb:CDK
gptkbp:discoveredBy gptkb:Paul_Nurse
gptkbp:enzymeClassification EC 2.7.11.22
gptkbp:foundIn eukaryotes
gptkbp:function regulation of cell cycle
https://www.w3.org/2000/01/rdf-schema#label Cyclin-dependent kinase
gptkbp:inhibitedBy CDK inhibitor protein
gptkbp:involves gptkb:cancer
apoptosis
differentiation
neurodegenerative diseases
cell division
developmental disorders
transcription regulation
gptkbp:modulatedBy phosphorylation
gptkbp:mutationAssociatedWith cell cycle defects
gptkbp:phosphorylates target proteins
gptkbp:proteinFamily CDK family
gptkbp:relatedTo cell cycle checkpoints
gptkbp:requires gptkb:cyclin
gptkbp:structure gptkb:protein
gptkbp:subunit catalytic subunit
regulatory subunit
gptkbp:target anticancer drugs
gptkbp:bfsParent gptkb:CDK
gptkbp:bfsLayer 7