Creutzfeldt–Jakob disease

URI: https://gptkb.org/entity/Creutzfeldt–Jakob_disease
GPTKB entity
Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:disease
neurodegenerative disease
prion disease
gptkbp:affects humans
central nervous system
gptkbp:casualties yes
gptkbp:category gptkb:disease
neurological disorder
rare disease
gptkbp:causedBy prions
gptkbp:diagnosedBy gptkb:EEG
MRI
CSF analysis
brain biopsy
gptkbp:firstDescribed 1920
https://www.w3.org/2000/01/rdf-schema#label Creutzfeldt–Jakob disease
gptkbp:ICD-10_code A81.0
gptkbp:medianSurvival less than 1 year
gptkbp:MeSH_ID D003456
gptkbp:namedAfter gptkb:Alfons_Maria_Jakob
gptkb:Hans_Gerhard_Creutzfeldt
gptkbp:OMIM 123400
gptkbp:prevalence 1 in 1,000,000 per year
gptkbp:prognosis poor
gptkbp:progression gptkb:fire
gptkbp:relatedTo gptkb:Gerstmann–Sträussler–Scheinker_syndrome
gptkb:bovine_spongiform_encephalopathy
gptkb:fatal_familial_insomnia
kuru
gptkbp:riskFactor consumption of contaminated beef (vCJD)
exposure to contaminated medical equipment
family history of prion disease
gptkbp:subspecies gptkb:familial_CJD
gptkb:iatrogenic_CJD
gptkb:sporadic_CJD
gptkb:variant_CJD
gptkbp:symptom gptkb:dementia
memory loss
muscle stiffness
ataxia
personality changes
myoclonus
visual disturbances
gptkbp:transmission hereditary
sporadic
iatrogenic
variant (vCJD)
gptkbp:treatment supportive care
gptkbp:bfsParent gptkb:Mike_Homer
gptkbp:bfsLayer 5