Creutzfeldt–Jakob disease

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:neurodegenerative_disease gptkb:prion_disease gptkb:disease
gptkbp:affects	humans central nervous system
gptkbp:casualties	yes
gptkbp:category	gptkb:neurological_disorder gptkb:disease gptkb:rare_disease
gptkbp:causedBy	prions
gptkbp:diagnosedBy	gptkb:EEG MRI CSF analysis brain biopsy
gptkbp:firstDescribed	1920
gptkbp:ICD-10_code	A81.0
gptkbp:medianSurvival	less than 1 year
gptkbp:MeSH_ID	D003456
gptkbp:namedAfter	gptkb:Alfons_Maria_Jakob gptkb:Hans_Gerhard_Creutzfeldt
gptkbp:OMIM	123400
gptkbp:prevalence	1 in 1,000,000 per year
gptkbp:prognosis	poor
gptkbp:progression	gptkb:fire
gptkbp:relatedTo	gptkb:Gerstmann–Sträussler–Scheinker_syndrome gptkb:bovine_spongiform_encephalopathy gptkb:fatal_familial_insomnia kuru
gptkbp:riskFactor	consumption of contaminated beef (vCJD) exposure to contaminated medical equipment family history of prion disease
gptkbp:subspecies	gptkb:familial_CJD gptkb:iatrogenic_CJD gptkb:sporadic_CJD gptkb:variant_CJD
gptkbp:symptom	gptkb:dementia memory loss muscle stiffness ataxia personality changes myoclonus visual disturbances
gptkbp:transmission	hereditary sporadic iatrogenic variant (vCJD)
gptkbp:treatment	supportive care
gptkbp:bfsParent	gptkb:Mike_Homer
gptkbp:bfsLayer	5
https://www.w3.org/2000/01/rdf-schema#label	Creutzfeldt–Jakob disease