Creatine Phosphokinase

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:activityRegulatedBy magnesium ions
pH
substrate concentration
gptkbp:alsoKnownAs gptkb:CK
gptkb:CPK
gptkbp:catalyzes conversion of creatine and ATP to phosphocreatine and ADP
gptkbp:discoveredIn 1960
gptkbp:EC_number 2.7.3.2
gptkbp:elevatedIn myocardial infarction
muscular dystrophy
rhabdomyolysis
myositis
gptkbp:foundIn gptkb:skeletal_muscle
brain tissue
heart tissue
gptkbp:gene gptkb:CKMT1
gptkb:CKMT2
gptkb:CKM
gptkb:CKB
gptkbp:hasIsoenzyme gptkb:CK-BB
gptkb:CK-MM
gptkb:CK-MB
https://www.w3.org/2000/01/rdf-schema#label Creatine Phosphokinase
gptkbp:measures blood tests
gptkbp:molecularWeight approximately 82 kDa
gptkbp:significance marker for heart attack
marker for muscle damage
gptkbp:structure dimer of M and B subunits
gptkbp:usedIn diagnosis of myocardial infarction
diagnosis of muscle diseases
gptkbp:bfsParent gptkb:CPK
gptkbp:bfsLayer 7