Clear cell adenocarcinoma of the ovary

URI: https://gptkb.org/entity/Clear_cell_adenocarcinoma_of_the_ovary
GPTKB entity
Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkbp:alternativeName gptkb:Ovarian_clear_cell_carcinoma
gptkbp:canBeMalignant malignant
gptkbp:firstDescribed 1973
gptkbp:hasChemoresistance platinum-based agents
gptkbp:hasCommonMarker gptkb:Napsin_A
gptkb:HNF-1β
gptkbp:hasEpidemiology more common in East Asia
gptkbp:hasFrequencyAmongOvarianCancers 5-10%
gptkbp:hasImmunohistochemistryProfile negative for ER
negative for PR
negative for WT1
positive for HNF-1β
positive for Napsin A
gptkbp:hasMetastasisSite gptkb:cancer
liver
lymph nodes
peritoneum
gptkbp:hasPrecursorLesion endometriosis
gptkbp:hasPrimarySite gptkb:testis
gptkbp:hasType clear cell
gptkbp:hasTypicalAgeOfOnset adulthood
gptkbp:histology tubulocystic, papillary, and solid patterns
https://www.w3.org/2000/01/rdf-schema#label Clear cell adenocarcinoma of the ovary
gptkbp:ICD-10_code C56
gptkbp:mutationAssociatedWith gptkb:ARID1A
gptkb:PIK3CA
TP53 (rarely)
gptkbp:prognosis stage at diagnosis
generally poor if advanced
residual tumor after surgery
gptkbp:riskFactor endometriosis
Japanese ethnicity
gptkbp:stageName gptkb:FIGO
gptkbp:symptom abdominal pain
abdominal distension
ascites
pelvic mass
gptkbp:synonym gptkb:Ovarian_clear_cell_adenocarcinoma
gptkb:Ovarian_clear_cell_carcinoma
gptkbp:treatment surgery
chemotherapy
gptkbp:WHOClassification Epithelial ovarian tumor
gptkbp:bfsParent gptkb:Clear_cell_adenocarcinoma
gptkbp:bfsLayer 5