Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cancer
gptkb:disease |
| gptkbp:affects |
Bile ducts
|
| gptkbp:alsoKnownAs |
Bile duct cancer
|
| gptkbp:canMetastasizeTo |
gptkb:Peritoneum
Liver Lung Lymph nodes |
| gptkbp:complication |
Metastasis
Liver failure Biliary obstruction Cholangitis |
| gptkbp:diagnosedBy |
Imaging
Biopsy Blood tests |
| gptkbp:firstDescribed |
1840
|
| gptkbp:hasBiomarker |
gptkb:KRAS_mutation
IDH1 mutation ARID1A mutation BAP1 mutation FGFR2 fusion |
| gptkbp:hasEpidemiology |
Incidence increases with age
Slight male predominance More common in Southeast Asia |
| gptkbp:hasTreatmentOption |
Palliative care
Liver transplantation |
| gptkbp:ICD-10_code |
C22.1
|
| gptkbp:incidence |
Rare
|
| gptkbp:originatedIn |
Epithelial cells of bile ducts
|
| gptkbp:prognosis |
Poor
|
| gptkbp:riskFactor |
gptkb:Hepatitis_B
gptkb:Hepatitis_C Cirrhosis Primary sclerosing cholangitis Chronic biliary inflammation Liver fluke infection |
| gptkbp:subspecies |
Distal cholangiocarcinoma
Intrahepatic cholangiocarcinoma Perihilar cholangiocarcinoma |
| gptkbp:symptom |
Fever
Weight loss Jaundice Abdominal pain |
| gptkbp:treatment |
gptkb:radiation_therapy
Surgery Chemotherapy Targeted therapy |
| gptkbp:bfsParent |
gptkb:Hepatic_Cancer
gptkb:Liver_Cancer gptkb:Liver_Tumors gptkb:D00351 gptkb:D008582 |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cholangiocarcinoma
|