Statements (50)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:cancer
gptkb:disease |
gptkbp:affects |
Bile ducts
|
gptkbp:alsoKnownAs |
Bile duct cancer
|
gptkbp:canMetastasizeTo |
gptkb:Peritoneum
Liver Lung Lymph nodes |
gptkbp:complication |
Metastasis
Liver failure Biliary obstruction Cholangitis |
gptkbp:diagnosedBy |
Imaging
Biopsy Blood tests |
gptkbp:firstDescribed |
1840
|
gptkbp:hasBiomarker |
gptkb:KRAS_mutation
IDH1 mutation ARID1A mutation BAP1 mutation FGFR2 fusion |
gptkbp:hasEpidemiology |
Incidence increases with age
Slight male predominance More common in Southeast Asia |
gptkbp:hasTreatmentOption |
Palliative care
Liver transplantation |
https://www.w3.org/2000/01/rdf-schema#label |
Cholangiocarcinoma
|
gptkbp:ICD-10_code |
C22.1
|
gptkbp:incidence |
Rare
|
gptkbp:originatedIn |
Epithelial cells of bile ducts
|
gptkbp:prognosis |
Poor
|
gptkbp:riskFactor |
gptkb:Hepatitis_B
gptkb:Hepatitis_C Cirrhosis Primary sclerosing cholangitis Chronic biliary inflammation Liver fluke infection |
gptkbp:subspecies |
Distal cholangiocarcinoma
Intrahepatic cholangiocarcinoma Perihilar cholangiocarcinoma |
gptkbp:symptom |
Fever
Weight loss Jaundice Abdominal pain |
gptkbp:treatment |
radiation therapy
Surgery Chemotherapy Targeted therapy |
gptkbp:bfsParent |
gptkb:D008582
|
gptkbp:bfsLayer |
6
|